Ismail K Jalili



Ismail Jalili is a retired consultant ophthalmic surgeon whose main focus of work now is in ophthalmic genetics with a particular emphasis on retinal dystrophies. This includes cone-rod and rod-cone macular dystrophies together with an acquired interest in enamel dysplasias and genetics of the CNNM4 gene. He continues to publish on this subject (link to publications) in addition to being a reviewer for several international journals.
His interest in multiple genetic associations commenced following work in the Middle East and in particular with the Order of St John in Jerusalem at the St. Johnís Eye Hospital and as a visiting professor at the King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia where the volume of genetic disorders encountered there greatly exceeded those encountered in the UK.
In addition to his genetic interest and work, he had over thirty years experience, predominantly in the UK National Health Service, but also in posts abroad. Prior to entering the field of ophthalmology, Dr Jalili had wide experience in major surgical specialities including general, cardio-thoracic, plastic, orthopaedic and plastic surgery at major UK teaching hospitals. His ophthalmic work included general medical ophthalmology and diabetic eye disease together with all types of ophthalmic surgery. He was also involved in screening programmes and in the prevention of visual disorders in childhood. (full cv link here) Since the 1980s his work also involved ophthalmic genetic research and this remains his main interest.






I am a fully accredited consultant ophthalmic surgeon on the GMC Specialists Register. I have thirty years experience in the provision of medico-legal reports spanning my career. As an expert witness, I cover both personal injuries and medical negligence.

My training in ophthalmology was preceded by four year training in non-ophthalmic surgical rotations which included accident and emergency, orthopaedics, general, cardio-thoracic, neuro and plastic surgery; all at teaching hospitals. This has enabled me to offer a multi-disciplinary approach and expertise to my clinical judgement and medico-legal work including medical negligence.

My ophthalmic training was in leading teaching hospitals in Cardiff, Sheffield and London teaching hospitals. It also included part-time fellowships in diabetic retinopathy (at the Retinal Diagnostic Unit) and glaucoma at the Glaucoma Unit at Moorfields Eye Hospital in addition to a three-month full-time course in neurology and neuro-ophthalmology at the National Hospital for Neurology, Queen Square.

My experience in ocular trauma and knowledge of a wide range of rare pathologies were greatly enhanced by working abroad at the Eye Specialist Hospital in Riyadh, Saudi Arabia and the St Johnís Ophthalmic Hospital, Jerusalem. In the latter I also set up a prevention programme for childhood blindness.

Following a period of research preparing for an MD, I completed 6 months training at the Professorial Unit of Moorfields Eye Hospital which focused on cataract and anterior segment and included training at the Cornea and Oncology Clinics

My practice as an ophthalmic surgeon in anterior segment surgery focused on cataract and with special clinics in paediatric ophthalmology, diabetic eye disease and glaucoma. I also pioneered a community based screening programmes for diabetic retinopathy in North Cheshire.

In terms of academic and managerial responsibilities, I held the position of departmental tutor for the Royal College of Ophthalmologists and an Audit Lead. I was also responsible for preparing a regional audit on the Cataract Treatment Centre in North Wales funded by the Welsh Office.

In addition to my clinical work, I continue my involvement in ophthalmic research. I have discovered and published a wide range of previously unrecognised new conditions among them the internationally recognised ĎJalili Syndromeí. The causative gene was found this year. On the latter, I am working in affiliation with the Ophthalmology Molecular Genetics Unit of Leeds University at St Jamesís Teaching Hospital which is undertaking a specially funded research programme on bio-mineralisation based on the Jalili syndrome. My work has also helped to establish new inroads in medico-legal, forensic medicine and paternity cases in the findings that members of inbred communities share identical patterns making DNA fingerprinting less reliable as a test. More detailed information on my experience is available on the website including the above book.

In addition to above I was involved in advising, as an elected local government councillor, on hospital development, health standards and scrutiny.



Ismail K Jalili 2000-2016